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In early times, pharmacy as well as the practice of medicine was most of the times mixed, often under the control of priests, irrespective if they were men or women, who assisted to the ill people with religious rites too. Many nations all over the world go on with the close connection of medicine, drugs, faith or religion. Specialization first appeared in the 8th century in the modern area around Baghdad. It spread little by little to Europe as alchemy.